Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

Long-term exposure to fine particulate matter (PM2.5) has been reported to be closely associated with the increased lung cancer risk in populations, but the mechanisms underlying PM-associated carcinogenesis are not yet clear. Previous studies have indicated that aberrant epigenetic alterations, suc...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Tian, Dongdong, He, Jun, Wang, Yimei, Zhang, Lijun, Cui, Lan, jia, Li, Zhang, Li, Li, Lizhong, Shu, Yulei, Yu, Shouzhong, Zhao, Jun, Yuan, Xiaoyan, Peng, Shuangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991485/
https://www.ncbi.nlm.nih.gov/pubmed/26942697
http://dx.doi.org/10.18632/oncotarget.7842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991485/
https://www.ncbi.nlm.nih.gov/pubmed/26942697
http://dx.doi.org/10.18632/oncotarget.7842

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