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Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation
Long-term exposure to fine particulate matter (PM2.5) has been reported to be closely associated with the increased lung cancer risk in populations, but the mechanisms underlying PM-associated carcinogenesis are not yet clear. Previous studies have indicated that aberrant epigenetic alterations, suc...
Autores principales: | Zhou, Wei, Tian, Dongdong, He, Jun, Wang, Yimei, Zhang, Lijun, Cui, Lan, jia, Li, Zhang, Li, Li, Lizhong, Shu, Yulei, Yu, Shouzhong, Zhao, Jun, Yuan, Xiaoyan, Peng, Shuangqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991485/ https://www.ncbi.nlm.nih.gov/pubmed/26942697 http://dx.doi.org/10.18632/oncotarget.7842 |
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