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Inhibition of estrogen biosynthesis enhances lymphoma growth in mice

Most lymphomas show higher incidence and poorer prognosis in males compared to females. However, the endocrine contribution to this gender difference is not entirely known. Here we show that castration accelerates lymphoma growth in C57BL6 male mice grafted with murine EG7 T cell lymphoma cells. How...

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Detalles Bibliográficos
Autores principales: Talaber, Gergely, Yakimchuk, Konstantin, Guan, Jiyu, Inzunza, Jose, Okret, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991487/
https://www.ncbi.nlm.nih.gov/pubmed/26943574
http://dx.doi.org/10.18632/oncotarget.7843