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Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

The resistance to chemotherapy and the tumor escape from host immunosurveillance are the main causes of the failure of anthracycline-based regimens in breast cancer, where an effective chemo-immunosensitizing strategy is lacking. The clinically used aminobisphosphonate zoledronic acid (ZA) reverses...

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Detalles Bibliográficos
Autores principales: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Pinzòn-Daza, Martha Leonor, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, De Rosa, Giuseppe, Caraglia, Michele, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991490/
https://www.ncbi.nlm.nih.gov/pubmed/26980746
http://dx.doi.org/10.18632/oncotarget.8012