Cargando…

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

The resistance to chemotherapy and the tumor escape from host immunosurveillance are the main causes of the failure of anthracycline-based regimens in breast cancer, where an effective chemo-immunosensitizing strategy is lacking. The clinically used aminobisphosphonate zoledronic acid (ZA) reverses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Pinzòn-Daza, Martha Leonor, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, De Rosa, Giuseppe, Caraglia, Michele, Riganti, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991490/ https://www.ncbi.nlm.nih.gov/pubmed/26980746 http://dx.doi.org/10.18632/oncotarget.8012

Ejemplares similares

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells
por: Kopecka, Joanna, et al.
Publicado: (2015)

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma
por: Salaroglio, Iris Chiara, et al.
Publicado: (2014)

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid
por: Porru, Manuela, et al.
Publicado: (2014)

Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells
por: Riganti, Chiara, et al.
Publicado: (2013)

iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
por: De Boo, Sara, et al.
Publicado: (2009)

Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells
por: Kopecka, Joanna, et al.
Publicado: (2015)

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells
por: Campia, Ivana, et al.
Publicado: (2015)

Highly Sensitive Immunoresistive Sensor for Point-Of-Care Screening for COVID-19
por: Li, Tianyi, et al.
Publicado: (2022)

P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors
por: Kopecka, Joanna, et al.
Publicado: (2016)

Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance
por: Belisario, Dimas Carolina, et al.
Publicado: (2020)

Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
por: Akman, Muhlis, et al.
Publicado: (2021)

ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer
por: Salaroglio, Iris C., et al.
Publicado: (2019)

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA
por: Coelho, Matthew A., et al.
Publicado: (2017)

Hybrid Self-Assembling Nanoparticles Encapsulating Zoledronic Acid: A Strategy for Fostering Their Clinical Use
por: Abate, Marianna, et al.
Publicado: (2022)

Chitosan-Based Polyelectrolyte Complexes for Doxorubicin and Zoledronic Acid Combined Therapy to Overcome Multidrug Resistance
por: Giarra, Simona, et al.
Publicado: (2018)

Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition
por: Gelsomino, Giada, et al.
Publicado: (2013)

Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
por: Salaroglio, Iris C., et al.
Publicado: (2018)

M2-TAMs promote immunoresistance in lung adenocarcinoma by enhancing METTL3-mediated m6A methylation
por: Wu, Lige, et al.
Publicado: (2022)

Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells
por: Gazzano, Elena, et al.
Publicado: (2018)

New Tetrahydroisoquinoline Derivatives Overcome Pgp Activity in Brain-Blood Barrier and Glioblastoma Multiforme in Vitro
por: Salaroglio, Iris Chiara, et al.
Publicado: (2018)

Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation
por: Arnoletti, Juan Pablo, et al.
Publicado: (2022)

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells
por: Borghese, Cinzia, et al.
Publicado: (2017)

Overcoming drug resistance in glioblastoma: new options in sight?
por: Kopecka, Joanna, et al.
Publicado: (2021)

Liposome armed with herpes virus-derived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines
por: Perillo, Emiliana, et al.
Publicado: (2015)

Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma
por: Godel, Martina, et al.
Publicado: (2020)

Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells
por: Kopecka, Joanna, et al.
Publicado: (2011)

Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells
por: Fathy Abd-Ellatef, Gamal-Eldein, et al.
Publicado: (2020)

Addressing the Real-World Challenges of Immunoresistance to Botulinum Neurotoxin A in Aesthetic Practice: Insights and Recommendations from a Panel Discussion in Hong Kong
por: Ho, Wilson W. S., et al.
Publicado: (2023)

Effects of Chrysotile Exposure in Human Bronchial Epithelial Cells: Insights into the Pathogenic Mechanisms of Asbestos-Related Diseases
por: Gulino, Giulia Rossana, et al.
Publicado: (2015)

Pretreatment of breast cancer cells with doxorubicin facilitates the subsequent uptake of zoledronic acid
por: Lefley, DV, et al.
Publicado: (2008)

Lipid Nanovectors to Deliver RNA Oligonucleotides in Cancer
por: Campani, Virginia, et al.
Publicado: (2016)

Albumin nanoformulations as an innovative solution to overcome doxorubicin chemoresistance
por: Bessone, Federica, et al.
Publicado: (2021)

A Comprehensive Evaluation of Sdox, a Promising H(2)S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors
por: Alov, Petko, et al.
Publicado: (2022)

A lysosome-targeted dextran-doxorubicin nanodrug overcomes doxorubicin-induced chemoresistance of myeloid leukemia
por: Zeng, Yunxin, et al.
Publicado: (2021)

Editorial: Novel therapeutic approaches to target drug resistant tumors
por: Riganti, Chiara, et al.
Publicado: (2023)

Comparative effects of free doxorubicin, liposome encapsulated doxorubicin and liposome co-encapsulated alendronate and doxorubicin (PLAD) on the tumor immunologic milieu in a mouse fibrosarcoma model
por: Islam, Md. Rakibul, et al.
Publicado: (2022)

Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein
por: Wu, Dapeng, et al.
Publicado: (2017)

Bisphosphonates and Cancer: What Opportunities from Nanotechnology?
por: De Rosa, Giuseppe, et al.
Publicado: (2013)

Zoledronic Acid Produces Combinatory Anti-Tumor Effects with Cisplatin on Mesothelioma by Increasing p53 Expression Levels
por: Okamoto, Shinya, et al.
Publicado: (2013)

Doxorubicin Encapsulation in Carbon Nanotubes Having Haeckelite or Stone–Wales Defects as Drug Carriers: A Molecular Dynamics Approach
por: Contreras, Leonor, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hoguqghajr71gisv655bb15rmh