Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

The tumor microenvironment is emerging as a key regulator of cancer growth and progression, however the exact mechanisms of interaction with the tumor are poorly understood. Whilst the majority of genomic profiling efforts thus far have focused on the tumor, here we investigate RNA-Seq as a hypothes...

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Detalles Bibliográficos
Autores principales: Bradford, James R., Wappett, Mark, Beran, Garry, Logie, Armelle, Delpuech, Oona, Brown, Henry, Boros, Joanna, Camp, Nicola J., McEwen, Robert, Mazzola, Anne Marie, D'Cruz, Celina, Barry, Simon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991491/
https://www.ncbi.nlm.nih.gov/pubmed/26980748
http://dx.doi.org/10.18632/oncotarget.8014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991491/
https://www.ncbi.nlm.nih.gov/pubmed/26980748
http://dx.doi.org/10.18632/oncotarget.8014

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