Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer

PURPOSE: We aimed to investigate the feasibility of droplet digital PCR (ddPCR) for the quantitative and dynamic detection of EGFR mutations and next generation sequencing (NGS) for screening EGFR-tyrosine kinase inhibitors (EGFR-TKIs) resistance-relevant mutations in circulating tumor DNA (ctDNA) f...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xue, Zhuo, Minglei, Ye, Xin, Bai, Hua, Wang, Zhijie, Sun, Yun, Zhao, Jun, An, Tongtong, Duan, Jianchun, Wu, Meina, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991494/
https://www.ncbi.nlm.nih.gov/pubmed/26989078
http://dx.doi.org/10.18632/oncotarget.8021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991494/
https://www.ncbi.nlm.nih.gov/pubmed/26989078
http://dx.doi.org/10.18632/oncotarget.8021

Ejemplares similares