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Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

The role of IL10 in the tumorigenesis of various cancer types is still controversial. Here, we found that increased IL10 levels are correlated with a poor prognosis in lung cancer patients. Moreover, IL10 levels were significantly increased in the lungs and serum of EGFR(L858R)- and Kras4b(G12D)-ind...

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Detalles Bibliográficos
Autores principales: Hsu, Tsung-I, Wang, Yi-Chang, Hung, Chia-Yang, Yu, Chun-Hui, Su, Wu-Chou, Chang, Wen-Chang, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991496/
https://www.ncbi.nlm.nih.gov/pubmed/26956044
http://dx.doi.org/10.18632/oncotarget.7894