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Positive feedback regulation between IL10 and EGFR promotes lung cancer formation
The role of IL10 in the tumorigenesis of various cancer types is still controversial. Here, we found that increased IL10 levels are correlated with a poor prognosis in lung cancer patients. Moreover, IL10 levels were significantly increased in the lungs and serum of EGFR(L858R)- and Kras4b(G12D)-ind...
Autores principales: | Hsu, Tsung-I, Wang, Yi-Chang, Hung, Chia-Yang, Yu, Chun-Hui, Su, Wu-Chou, Chang, Wen-Chang, Hung, Jan-Jong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991496/ https://www.ncbi.nlm.nih.gov/pubmed/26956044 http://dx.doi.org/10.18632/oncotarget.7894 |
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