Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins

Micro-RNAs (miRs) represent an innovative class of genes that act as regulators of gene expression. Recently, the aberrant expression of several miRs has been associated with different types of cancers. In this study, we show that miR301 inhibition influences PI3K-Akt pathway activity. Akt overexpre...

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Detalles Bibliográficos
Autores principales: Jain, Mayur V., Shareef, Ahmad, Likus, Wirginia, Cieślar-Pobuda, Artur, Ghavami, Saeid, Łos, Marek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991504/
https://www.ncbi.nlm.nih.gov/pubmed/26967567
http://dx.doi.org/10.18632/oncotarget.7996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991504/
https://www.ncbi.nlm.nih.gov/pubmed/26967567
http://dx.doi.org/10.18632/oncotarget.7996

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