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Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins
Micro-RNAs (miRs) represent an innovative class of genes that act as regulators of gene expression. Recently, the aberrant expression of several miRs has been associated with different types of cancers. In this study, we show that miR301 inhibition influences PI3K-Akt pathway activity. Akt overexpre...
Autores principales: | Jain, Mayur V., Shareef, Ahmad, Likus, Wirginia, Cieślar-Pobuda, Artur, Ghavami, Saeid, Łos, Marek J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991504/ https://www.ncbi.nlm.nih.gov/pubmed/26967567 http://dx.doi.org/10.18632/oncotarget.7996 |
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