ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

Drug-induced aberrant DNA methylation is the first identified epigenetic marker involved in chemotherapy resistance. Understanding how the aberrant DNA methylation is acquired would impact cancer treatment in theory and practice. In this study we systematically investigated whether and how ERα prope...

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Detalles Bibliográficos
Autores principales: Si, Xinxin, Liu, Yue, Lv, Jinghuan, Ding, Haijian, Zhang, Xin A., Shao, Lipei, Yang, Nan, Cheng, He, Sun, Luan, Zhu, Dongliang, Yang, Yin, Li, Andi, Han, Xiao, Sun, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991505/
https://www.ncbi.nlm.nih.gov/pubmed/26980709
http://dx.doi.org/10.18632/oncotarget.8038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991505/
https://www.ncbi.nlm.nih.gov/pubmed/26980709
http://dx.doi.org/10.18632/oncotarget.8038

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