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Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

[Image: see text] We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitr...

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Detalles Bibliográficos
Autores principales: Montgomery, Thomas D., Rawal, Viresh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991562/
https://www.ncbi.nlm.nih.gov/pubmed/26824482
http://dx.doi.org/10.1021/acs.orglett.5b03708