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A Single-Dose, Single-Period Pharmacokinetic Assessment of an Extended-Release Orally Disintegrating Tablet of Methylphenidate in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

Objective: To determine the pharmacokinetic (PK) profile of a proprietary formulation of methylphenidate (MPH) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) in a phase 1 study. Methylphenidate extended-release orally disintegrating tablets (MPH XR-ODTs) combine two...

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Detalles Bibliográficos
Autores principales: Childress, Ann, Newcorn, Jeffrey, Stark, Jeffrey G., McMahen, Russ, Tengler, Mark, Sikes, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991613/
https://www.ncbi.nlm.nih.gov/pubmed/27228207
http://dx.doi.org/10.1089/cap.2015.0261