Kindlin1 regulates microtubule function to ensure normal mitosis

Loss of Kindlin 1 (Kin1) results in the skin blistering disorder Kindler Syndrome (KS), whose symptoms also include skin atrophy and reduced keratinocyte proliferation. Kin1 binds to integrins to modulate their activation and more recently it has been shown to regulate mitotic spindles and cell surv...

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Detalles Bibliográficos
Autores principales: Patel, Hitesh, Stavrou, Ifigeneia, Shrestha, Roshan L., Draviam, Viji, Frame, Margaret C., Brunton, Valerie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991666/
https://www.ncbi.nlm.nih.gov/pubmed/26993041
http://dx.doi.org/10.1093/jmcb/mjw009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991666/
https://www.ncbi.nlm.nih.gov/pubmed/26993041
http://dx.doi.org/10.1093/jmcb/mjw009

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