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Embryonic hematopoiesis in vertebrate somites gives rise to definitive hematopoietic stem cells

Hematopoietic stem cells (HSCs) replenish all types of blood cells. It is debating whether HSCs in adults solely originate from the aorta-gonad-mesonephros (AGM) region, more specifically, the dorsal aorta, during embryogenesis. Here, we report that somite hematopoiesis, a previously unwitnessed hem...

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Detalles Bibliográficos
Autores principales: Qiu, Juhui, Fan, Xiaoying, Wang, Yixia, Jin, Hongbin, Song, Yixiao, Han, Yang, Huang, Shenghong, Meng, Yaping, Tang, Fuchou, Meng, Anming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991667/
https://www.ncbi.nlm.nih.gov/pubmed/27252540
http://dx.doi.org/10.1093/jmcb/mjw024