Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1

Intervertebral disk degeneration (IDD) is a major cause of low back pain and an important socioeconomic burden. Degradation of the extracellular matrix (ECM) of nucleus pulposus (NP) cells in the interverterbal disk is important for IDD. Stress of a suitable frequency and amplitude promotes the synt...

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Detalles Bibliográficos
Autores principales: Gao, Gongming, He, Jin, Nong, Luming, Xie, Hua, Huang, Yongjing, Xu, Nanwei, Zhou, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991676/
https://www.ncbi.nlm.nih.gov/pubmed/27484337
http://dx.doi.org/10.3892/mmr.2016.5549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991676/
https://www.ncbi.nlm.nih.gov/pubmed/27484337
http://dx.doi.org/10.3892/mmr.2016.5549

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