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Trichostatin A increases the TIMP-1/MMP ratio to protect against osteoarthritis in an animal model of the disease
The histone deacetylase inhibitor trichostatin A (TSA) has been demonstrated to alleviate certain symptoms associated with osteoarthritis (OA). However, the exact mechanisms underlying this protective effect remain to be elucidated. The present study therefore examined the effects of TSA on the expr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991690/ https://www.ncbi.nlm.nih.gov/pubmed/27431944 http://dx.doi.org/10.3892/mmr.2016.5523 |