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Slit2-Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E-cadherin

Whether Slit homologue 2 (Slit2) inhibits or promotes tumor cell migration remains controversial, and the role of Slit2-Roundabout 1 (Robo1) signaling in oral cancer remains to be fully elucidated. The aim of the present study was to investigate the role of Slit2-Robo1 signaling in the adhesion, inv...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Zhou, Feng-Li, Li, Wei-Ping, Wang, Jing, Wang, Li-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991736/
https://www.ncbi.nlm.nih.gov/pubmed/27431199
http://dx.doi.org/10.3892/mmr.2016.5518