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The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). Here, we have used primary human monocyte-derived macrophages differentiate...

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Detalles Bibliográficos
Autores principales: Badia, Roger, Pujantell, Maria, Riveira-Muñoz, Eva, Puig, Teresa, Torres-Torronteras, Javier, Martí, Ramón, Clotet, Bonaventura, Ampudia, Rosa M., Vives-Pi, Marta, Esté, José A., Ballana, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991798/
https://www.ncbi.nlm.nih.gov/pubmed/27541004
http://dx.doi.org/10.1371/journal.ppat.1005829