Cargando…

The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid

The APOBEC3 (A3) cytidine deaminases are antiretroviral proteins, whose targets include human immunodeficiency virus type-1 (HIV-1). Their incorporation into viral particles is critical for antiviral activity and is driven by interactions with the RNA molecules that are packaged into virions. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: York, Ashley, Kutluay, Sebla B., Errando, Manel, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991800/
https://www.ncbi.nlm.nih.gov/pubmed/27541140
http://dx.doi.org/10.1371/journal.ppat.1005833