Cardiac β(2)-Adrenergic Receptor Phosphorylation at Ser(355/356) Regulates Receptor Internalization and Functional Resensitization

Previous studies have demonstrated that β(2)-adrenergic receptors (β(2)ARs) can be phosphorylated by G protein-coupled receptor kinases (GRKs) and protein kinase A (PKA), affecting β(2)AR internalization and desensitization. However, the exact physiological function of β(2)ARs in cardiomyocytes is u...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Xiaofang, Gu, Xuejiang, Zhao, Ru, Zheng, Qingqing, Li, Lan, Yang, Wenbing, Ding, Lu, Xue, Feng, Fan, Junming, Gong, Yongsheng, Wang, Yongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991819/
https://www.ncbi.nlm.nih.gov/pubmed/27541735
http://dx.doi.org/10.1371/journal.pone.0161373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991819/
https://www.ncbi.nlm.nih.gov/pubmed/27541735
http://dx.doi.org/10.1371/journal.pone.0161373

Ejemplares similares