Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing

The application of next-generation sequencing to estimate genetic diversity of Plasmodium falciparum, the most lethal malaria parasite, has proved challenging due to the skewed AT-richness [∼80.6% (A + T)] of its genome and the lack of technology to assemble highly polymorphic subtelomeric regions t...

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Detalles Bibliográficos
Autores principales: Vembar, Shruthi Sridhar, Seetin, Matthew, Lambert, Christine, Nattestad, Maria, Schatz, Michael C., Baybayan, Primo, Scherf, Artur, Smith, Melissa Laird
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991835/
https://www.ncbi.nlm.nih.gov/pubmed/27345719
http://dx.doi.org/10.1093/dnares/dsw022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991835/
https://www.ncbi.nlm.nih.gov/pubmed/27345719
http://dx.doi.org/10.1093/dnares/dsw022

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