Cargando…
Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing
The application of next-generation sequencing to estimate genetic diversity of Plasmodium falciparum, the most lethal malaria parasite, has proved challenging due to the skewed AT-richness [∼80.6% (A + T)] of its genome and the lack of technology to assemble highly polymorphic subtelomeric regions t...
Autores principales: | Vembar, Shruthi Sridhar, Seetin, Matthew, Lambert, Christine, Nattestad, Maria, Schatz, Michael C., Baybayan, Primo, Scherf, Artur, Smith, Melissa Laird |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991835/ https://www.ncbi.nlm.nih.gov/pubmed/27345719 http://dx.doi.org/10.1093/dnares/dsw022 |
Ejemplares similares
-
Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression
por: Vembar, Shruthi S, et al.
Publicado: (2014) -
The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages
por: Vembar, Shruthi Sridhar, et al.
Publicado: (2015) -
Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems‐wide studies pave the way
por: Vembar, Shruthi Sridhar, et al.
Publicado: (2016) -
Telomeric Heterochromatin in Plasmodium falciparum
por: Hernandez-Rivas, Rosaura, et al.
Publicado: (2010) -
Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite Plasmodium falciparum
por: Herrera‐Solorio, Abril Marcela, et al.
Publicado: (2019)