Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking

Alzheimer’s disease (AD) is a chronic neurodegenerative disease which leads to the gradual loss of neuronal cells. Several hypotheses for AD exists (e.g., cholinergic, amyloid, tau hypotheses, etc.). As per the cholinergic hypothesis, the deficiency of choline is responsible for AD; therefore, the i...

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Detalles Bibliográficos
Autores principales: Simeon, Saw, Anuwongcharoen, Nuttapat, Shoombuatong, Watshara, Malik, Aijaz Ahmad, Prachayasittikul, Virapong, Wikberg, Jarl E.S., Nantasenamat, Chanin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991866/
https://www.ncbi.nlm.nih.gov/pubmed/27602288
http://dx.doi.org/10.7717/peerj.2322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991866/
https://www.ncbi.nlm.nih.gov/pubmed/27602288
http://dx.doi.org/10.7717/peerj.2322

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