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Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation

Background. Mammalian hibernation in thirteen-lined ground squirrels (Ictidomys tridecemlineatus) is characterized by dramatic changes on a physiological and molecular level. During hibernation, mammalian hearts show a propensity to hypertrophy due to the need for increasing contractility to pump co...

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Detalles Bibliográficos
Autores principales: Zhang, Yichi, Aguilar, Oscar A., Storey, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991874/
https://www.ncbi.nlm.nih.gov/pubmed/27602284
http://dx.doi.org/10.7717/peerj.2317