Cargando…

Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMR

Proteins are synthesized in cells by ribosomes and, in parallel, prepared for folding or targeting. While ribosomal protein synthesis is progressing, the nascent chain exposes amino-terminal signal sequences or transmembrane domains that mediate interactions with specific interaction partners, such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lange, Sascha, Franks, W. Trent, Rajagopalan, Nandhakishore, Döring, Kristina, Geiger, Michel A., Linden, Arne, van Rossum, Barth-Jan, Kramer, Günter, Bukau, Bernd, Oschkinat, Hartmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991931/ https://www.ncbi.nlm.nih.gov/pubmed/27551685 http://dx.doi.org/10.1126/sciadv.1600379

Ejemplares similares

DNP-Enhanced MAS NMR of Bovine Serum Albumin Sediments and Solutions
por: Ravera, Enrico, et al.
Publicado: (2014)

A software framework for analysing solid-state MAS NMR data
por: Stevens, Tim J., et al.
Publicado: (2011)

DNP‐Supported Solid‐State NMR Spectroscopy of Proteins Inside Mammalian Cells
por: Narasimhan, Siddarth, et al.
Publicado: (2019)

MAS NMR detection of hydrogen bonds for protein secondary structure characterization
por: Friedrich, Daniel, et al.
Publicado: (2020)

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States
por: Uluca, Boran, et al.
Publicado: (2018)

Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR
por: Goldberga, Ieva, et al.
Publicado: (2019)

Electron-decoupled MAS DNP with N@C(60)
por: Alaniva, Nicholas, et al.
Publicado: (2023)

The ribosome modulates folding inside the ribosomal exit tunnel
por: Wruck, Florian, et al.
Publicado: (2021)

Targeted DNP for biomolecular solid-state NMR
por: Gauto, Diego, et al.
Publicado: (2021)

The surface chemistry of a nanocellulose drug carrier unravelled by MAS-DNP
por: Kumar, Akshay, et al.
Publicado: (2020)

Optimizing chemistry at the surface of prodrug-loaded cellulose nanofibrils with MAS-DNP
por: Kumar, Akshay, et al.
Publicado: (2023)

The Effect of Disorder on Endogenous MAS-DNP: Study of Silicate Glasses and Crystals
por: Thomas, Brijith, et al.
Publicado: (2023)

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
por: Erlendsson, Simon, et al.
Publicado: (2017)

Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles
por: Becker-Baldus, Johanna, et al.
Publicado: (2023)

Cotranslational Protein Folding inside the Ribosome Exit Tunnel
por: Nilsson, Ola B., et al.
Publicado: (2015)

Transmembrane but not soluble helices fold inside the ribosome tunnel
por: Bañó-Polo, Manuel, et al.
Publicado: (2018)

Polymorphs of Theophylline Characterized by DNP Enhanced Solid-State NMR
por: Pinon, Arthur C., et al.
Publicado: (2015)

Microfluidic Overhauser DNP chip for signal-enhanced compact NMR
por: Kiss, Sebastian Z., et al.
Publicado: (2021)

Assignment and secondary structure of the YadA membrane protein by solid-state MAS NMR
por: Shahid, Shakeel A., et al.
Publicado: (2012)

Selective high-resolution DNP-enhanced NMR of biomolecular binding sites
por: Marin-Montesinos, Ildefonso, et al.
Publicado: (2019)

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide
por: Separovic, Frances, et al.
Publicado: (2022)

MAS NMR Investigation of Molecular Order in an Ionic Liquid Crystal
por: Mann, Sarah K., et al.
Publicado: (2020)

DNP 2017
Publicado: (2017)

An Enhanced Actualized DNP Model to Improve DNP Project Placements, Rigor, and Completion
por: VanderKooi, Marie E., et al.
Publicado: (2018)

Structural analysis of cross-linked poly(vinyl alcohol) using high-field DNP-NMR
por: Kanda, Taiji, et al.
Publicado: (2020)

Hierarchy of the Components in Spray-Dried, Protein-Excipient Particles Using DNP-Enhanced NMR Spectroscopy
por: Berruyer, Pierrick, et al.
Publicado: (2023)

In-Cell NMR of Intact Mammalian Cells Preserved with the Cryoprotectants DMSO and Glycerol Have Similar DNP Performance
por: Xiao, Yiling, et al.
Publicado: (2022)

Observation of glucose-6-phosphate anomeric exchange in real-time using dDNP hyperpolarised NMR
por: Uppala, Sivaranjan, et al.
Publicado: (2020)

Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells
por: Kragelj, Jaka, et al.
Publicado: (2023)

Leadership and systems improvement for the DNP
por: Armstrong, Gail, et al.
Publicado: (2019)

Inside the LHC tunnel
por: Brice, Maximilien
Publicado: (2023)

Inside the LEP tunnel
por: Philippe Dinault
Publicado: (1991)

Inside the SPS tunnel
por: CERN PhotoLab
Publicado: (1976)

Inside the PS tunnel
Publicado: (1974)

Inside the LHC Tunnel
por: Hoch, Michael
Publicado: (2008)

Inside the LHC tunnel
por: Hoch, Michael
Publicado: (2008)

Optimisation of (1)H PMLG homonuclear decoupling at 60 kHz MAS to enable (15)N–(1)H through-bond heteronuclear correlation solid-state NMR spectroscopy
por: Tognetti, Jacqueline, et al.
Publicado: (2022)

Correction: Optimisation of (1)H PMLG homonuclear decoupling at 60 kHz MAS to enable (15)N–(1)H through-bond heteronuclear correlation solid-state NMR spectroscopy
por: Tognetti, Jacqueline, et al.
Publicado: (2022)

Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-enhanced solid-state NMR
por: Jakdetchai, Orawan, et al.
Publicado: (2021)

Ultrafast 2D (1)H–(1)H NMR spectroscopy of DNP-hyperpolarised substrates for the analysis of mixtures
por: Singh, Kawarpal, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9gfci4r8iccm1usv9ugh85s7b6