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The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily...

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Detalles Bibliográficos
Autores principales: Van Vranken, Jonathan G, Jeong, Mi-Young, Wei, Peng, Chen, Yu-Chan, Gygi, Steven P, Winge, Dennis R, Rutter, Jared
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991935/
https://www.ncbi.nlm.nih.gov/pubmed/27540631
http://dx.doi.org/10.7554/eLife.17828