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Contributions of p38 and ERK to the antinociceptive effects of TGF-β1 in chronic constriction injury-induced neuropathic rats

BACKGROUND: Transforming growth factor-βs (TGF-βs) are a group of multifunctional proteins that have neuroprotective roles in various experimental models. We previously reported that intrathecal (i.t.) injections of TGF-β1 significantly inhibit neuropathy-induced thermal hyperalgesia, spinal microgl...

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Detalles Bibliográficos
Autores principales: Chen, Nan-Fu, Chen, Wu-Fu, Sung, Chun-Sung, Lu, Ching-Hsiang, Chen, Chun-Lin, Hung, Han-Chun, Feng, Chien-Wei, Chen, Chun-Hong, Tsui, Kuan-Hao, Kuo, Hsiao-Mei, Wang, Hui-Min David, Wen, Zhi-Hong, Huang, Shi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991976/
https://www.ncbi.nlm.nih.gov/pubmed/27541934
http://dx.doi.org/10.1186/s10194-016-0665-2