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High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia

Diets high in fat (HFD) are known to cause an immune response in the periphery as well as the central nervous system. In peripheral adipose tissue, this immune response is primarily mediated by macrophages that are recruited to the tissue. Similarly, reactivity of microglia, the innate immune cells...

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Detalles Bibliográficos
Autores principales: Baufeld, Caroline, Osterloh, Anja, Prokop, Stefan, Miller, Kelly R., Heppner, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992033/
https://www.ncbi.nlm.nih.gov/pubmed/27393312
http://dx.doi.org/10.1007/s00401-016-1595-4