Cargando…

Asymmetric counteranion-directed Lewis acid organocatalysis for the scalable cyanosilylation of aldehydes

Due to the high versatility of chiral cyanohydrins, the catalytic asymmetric cyanation reaction of carbonyl compounds has attracted widespread interest. However, efficient protocols that function at a preparative scale with low catalyst loading are still rare. Here, asymmetric counteranion-directed...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhipeng, Bae, Han Yong, Guin, Joyram, Rabalakos, Constantinos, van Gemmeren, Manuel, Leutzsch, Markus, Klussmann, Martin, List, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992067/
https://www.ncbi.nlm.nih.gov/pubmed/27530470
http://dx.doi.org/10.1038/ncomms12478