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Asymmetric counteranion-directed Lewis acid organocatalysis for the scalable cyanosilylation of aldehydes
Due to the high versatility of chiral cyanohydrins, the catalytic asymmetric cyanation reaction of carbonyl compounds has attracted widespread interest. However, efficient protocols that function at a preparative scale with low catalyst loading are still rare. Here, asymmetric counteranion-directed...
Autores principales: | Zhang, Zhipeng, Bae, Han Yong, Guin, Joyram, Rabalakos, Constantinos, van Gemmeren, Manuel, Leutzsch, Markus, Klussmann, Martin, List, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992067/ https://www.ncbi.nlm.nih.gov/pubmed/27530470 http://dx.doi.org/10.1038/ncomms12478 |
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