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Dynamic clonal equilibrium and predetermined cancer risk in Barrett's oesophagus

Surveillance of Barrett's oesophagus allows us to study the evolutionary dynamics of a human neoplasm over time. Here we use multicolour fluorescence in situ hybridization on brush cytology specimens, from two time points with a median interval of 37 months in 195 non-dysplastic Barrett's...

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Detalles Bibliográficos
Autores principales: Martinez, Pierre, Timmer, Margriet R., Lau, Chiu T., Calpe, Silvia, Sancho-Serra, Maria del Carmen, Straub, Danielle, Baker, Ann-Marie, Meijer, Sybren L., Kate, Fiebo J. W. ten, Mallant-Hent, Rosalie C., Naber, Anton H. J., van Oijen, Arnoud H. A. M., Baak, Lubbertus C., Scholten, Pieter, Böhmer, Clarisse J. M., Fockens, Paul, Bergman, Jacques J. G. H. M., Maley, Carlo C., Graham, Trevor A., Krishnadath, Kausilia K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992167/
https://www.ncbi.nlm.nih.gov/pubmed/27538785
http://dx.doi.org/10.1038/ncomms12158