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Dynamic clonal equilibrium and predetermined cancer risk in Barrett's oesophagus
Surveillance of Barrett's oesophagus allows us to study the evolutionary dynamics of a human neoplasm over time. Here we use multicolour fluorescence in situ hybridization on brush cytology specimens, from two time points with a median interval of 37 months in 195 non-dysplastic Barrett's...
Autores principales: | Martinez, Pierre, Timmer, Margriet R., Lau, Chiu T., Calpe, Silvia, Sancho-Serra, Maria del Carmen, Straub, Danielle, Baker, Ann-Marie, Meijer, Sybren L., Kate, Fiebo J. W. ten, Mallant-Hent, Rosalie C., Naber, Anton H. J., van Oijen, Arnoud H. A. M., Baak, Lubbertus C., Scholten, Pieter, Böhmer, Clarisse J. M., Fockens, Paul, Bergman, Jacques J. G. H. M., Maley, Carlo C., Graham, Trevor A., Krishnadath, Kausilia K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992167/ https://www.ncbi.nlm.nih.gov/pubmed/27538785 http://dx.doi.org/10.1038/ncomms12158 |
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