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Orchestrated activation of mGluR5 and CB(1) promotes neuroprotection
The metabotropic glutamate receptor 5 (mGluR5) and the cannabinoid receptor 1 (CB(1)) exhibit a functional interaction, as CB(1) regulates pre-synaptic glutamate release and mGluR5 activation increases endocannabinoid synthesis at the post-synaptic site. Since both mGluR5 and CB(1) promote neuroprot...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992217/ https://www.ncbi.nlm.nih.gov/pubmed/27543109 http://dx.doi.org/10.1186/s13041-016-0259-6 |