An activity canyon characterization of the pharmacological topography

BACKGROUND: Highly chemically similar drugs usually possess similar biological activities, but sometimes, small changes in chemistry can result in a large difference in biological effects. Chemically similar drug pairs that show extreme deviations in activity represent distinctive drug interactions...

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Detalles Bibliográficos
Autores principales: Kulkarni, Varsha S., Wild, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992238/
https://www.ncbi.nlm.nih.gov/pubmed/27547247
http://dx.doi.org/10.1186/s13321-016-0153-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992238/
https://www.ncbi.nlm.nih.gov/pubmed/27547247
http://dx.doi.org/10.1186/s13321-016-0153-3

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