Cargando…
An activity canyon characterization of the pharmacological topography
BACKGROUND: Highly chemically similar drugs usually possess similar biological activities, but sometimes, small changes in chemistry can result in a large difference in biological effects. Chemically similar drug pairs that show extreme deviations in activity represent distinctive drug interactions...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992238/ https://www.ncbi.nlm.nih.gov/pubmed/27547247 http://dx.doi.org/10.1186/s13321-016-0153-3 |