Prolactin-induced PAK1 tyrosyl phosphorylation promotes FAK dephosphorylation, breast cancer cell motility, invasion and metastasis

BACKGROUND: The serine/threonine kinase PAK1 is an important regulator of cell motility. Both PAK1 and the hormone/cytokine prolactin (PRL) have been implicated in breast cancer cell motility, however, the exact mechanisms guiding PRL/PAK1 signaling in breast cancer cells have not been fully elucida...

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Detalles Bibliográficos
Autores principales: Hammer, Alan, Diakonova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992334/
https://www.ncbi.nlm.nih.gov/pubmed/27542844
http://dx.doi.org/10.1186/s12860-016-0109-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992334/
https://www.ncbi.nlm.nih.gov/pubmed/27542844
http://dx.doi.org/10.1186/s12860-016-0109-5

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