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An in vitro study on the genotoxic effect of substituted furans in cells transfected with human metabolizing enzymes: 2,5-dimethylfuran and furfuryl alcohol

2,5-Dimethylfuran (DMF) and furfuryl alcohol (FFA) are two substituted furans that are formed during the processing of foods and have also been used as food flavorings. DMF and FFA are proposed to be bioactivated by human sulfotransferases (SULTs) which are not expressed in conventional cell lines u...

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Detalles Bibliográficos
Autores principales: Huffman, Minor P., Høie, Anja H., Svendsen, Camilla, Brunborg, Gunnar, Murkovic, Michael, Glatt, Hansruedi, Husøy, Trine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992344/
https://www.ncbi.nlm.nih.gov/pubmed/27226491
http://dx.doi.org/10.1093/mutage/gew025