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An in vitro study on the genotoxic effect of substituted furans in cells transfected with human metabolizing enzymes: 2,5-dimethylfuran and furfuryl alcohol
2,5-Dimethylfuran (DMF) and furfuryl alcohol (FFA) are two substituted furans that are formed during the processing of foods and have also been used as food flavorings. DMF and FFA are proposed to be bioactivated by human sulfotransferases (SULTs) which are not expressed in conventional cell lines u...
Autores principales: | Huffman, Minor P., Høie, Anja H., Svendsen, Camilla, Brunborg, Gunnar, Murkovic, Michael, Glatt, Hansruedi, Husøy, Trine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992344/ https://www.ncbi.nlm.nih.gov/pubmed/27226491 http://dx.doi.org/10.1093/mutage/gew025 |
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