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Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases

Neurons are extremely energy demanding cells and highly dependent on the mitochondrial oxidative phosphorylation (OXPHOS) system. Mitochondria generate the energetic potential via the respiratory complexes I to IV, which constitute the electron transport chain (ETC), together with complex V. These r...

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Detalles Bibliográficos
Autores principales: Giachin, Gabriele, Bouverot, Romain, Acajjaoui, Samira, Pantalone, Serena, Soler-López, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992684/
https://www.ncbi.nlm.nih.gov/pubmed/27597947
http://dx.doi.org/10.3389/fmolb.2016.00043