Cargando…
Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
HIGHLIGHTS: Compounds that interact with multiple targets but minimally with the cytochrome P450 system (CYP) address the many factors leading to neurodegeneration. Acetyl- and Butyryl-cholineEsterases (AChE, BChE) and Monoamine Oxidases A/B (MAO A, MAO B) are targets for Multi-Target Designed Ligan...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992697/ https://www.ncbi.nlm.nih.gov/pubmed/27597816 http://dx.doi.org/10.3389/fnins.2016.00375 |