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PSM-Mec—A Virulence Determinant that Connects Transcriptional Regulation, Virulence, and Antibiotic Resistance in Staphylococci

PSM-mec is a secreted virulence factor that belongs to the phenol-soluble modulin (PSM) family of amphipathic, alpha-helical peptide toxins produced by Staphylococcus species. All known PSMs are core genome-encoded with the exception of PSM-mec, whose gene is found in specific sub-types of SCCmec me...

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Detalles Bibliográficos
Autores principales: Qin, Li, McCausland, Joshua W., Cheung, Gordon Y. C., Otto, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992726/
https://www.ncbi.nlm.nih.gov/pubmed/27597849
http://dx.doi.org/10.3389/fmicb.2016.01293