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Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-κB Pathway and TNF-α

Syndecan-1 (SDC1), with a long variable ectodomain carrying heparan sulfate chains, participates in many steps of inflammatory responses. But reports about the efforts of SDC1's unshedding ectodomain on intestinal epithelial inflammation and the precise underlying mechanism are limited. In our...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Wang, Zhongqiu, Liu, Jun, Zhang, Zhenyu, Chen, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992761/
https://www.ncbi.nlm.nih.gov/pubmed/27579035
http://dx.doi.org/10.1155/2016/6421351