Unraveling the Effect of Immunogenicity on the PK/PD, Efficacy, and Safety of Therapeutic Proteins

Biologics have emerged as a powerful and diverse class of molecular and cell-based therapies that are capable of replacing enzymes, editing genomes, targeting tumors, and more. As this complex array of tools arises a distinct set of challenges is rarely encountered in the development of small molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Alison, Manoli, Hugh, Jaw, Stacey, Frutoz, Kimberley, Epstein, Alan L., Khawli, Leslie A., Theil, Frank-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992793/
https://www.ncbi.nlm.nih.gov/pubmed/27579329
http://dx.doi.org/10.1155/2016/2342187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992793/
https://www.ncbi.nlm.nih.gov/pubmed/27579329
http://dx.doi.org/10.1155/2016/2342187

Ejemplares similares