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In Silico Prediction of Gamma-Aminobutyric Acid Type-A Receptors Using Novel Machine-Learning-Based SVM and GBDT Approaches

Gamma-aminobutyric acid type-A receptors (GABA(A)Rs) belong to multisubunit membrane spanning ligand-gated ion channels (LGICs) which act as the principal mediators of rapid inhibitory synaptic transmission in the human brain. Therefore, the category prediction of GABA(A)Rs just from the protein ami...

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Detalles Bibliográficos
Autores principales: Liao, Zhijun, Huang, Yong, Yue, Xiaodong, Lu, Huijuan, Xuan, Ping, Ju, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992803/
https://www.ncbi.nlm.nih.gov/pubmed/27579307
http://dx.doi.org/10.1155/2016/2375268