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Robust neuroprotective effects of 2-((2-oxopropanoyl)oxy)-4-(trifluoromethyl)benzoic acid (OPTBA), a HTB/pyruvate ester, in the postischemic rat brain

Postischemic brain damage in stroke is proceded with complicated pathological events, and so multimodal drug treatments may offer better therapeutic means for improving clinical outcomes. Here, we report robust neuroprotective effects of a novel compound, 2-((2-oxopropanoyl)oxy)-4-(trifluoromethyl)b...

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Detalles Bibliográficos
Autores principales: Kim, Seung-Woo, Lee, Hye-Kyung, Kim, Il-Doo, Lee, Hahnbie, Luo, Lidan, Park, Ju-Young, Yoon, Sung-Hwa, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992820/
https://www.ncbi.nlm.nih.gov/pubmed/27545301
http://dx.doi.org/10.1038/srep31843