Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

Starting from only a few cells, current whole genome amplification (WGA) methods provide enough DNA to perform massively parallel sequencing (MPS). Unfortunately, all current WGA methods introduce representation bias which limits detection of copy number aberrations (CNAs) smaller than 3 Mb. A recen...

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Detalles Bibliográficos
Autores principales: Deleye, Lieselot, De Coninck, Dieter, Dheedene, Annelies, De Sutter, Petra, Menten, Björn, Deforce, Dieter, Van Nieuwerburgh, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992833/
https://www.ncbi.nlm.nih.gov/pubmed/27546482
http://dx.doi.org/10.1038/srep31825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992833/
https://www.ncbi.nlm.nih.gov/pubmed/27546482
http://dx.doi.org/10.1038/srep31825

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