Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

Human immunodeficiency virus type 1 (HIV-1) groups M, N, O, and P are the result of independent zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting great apes in Africa. Among these, only Vpu proteins of pandemic HIV-1 group M strains evolved potent activity against the restri...

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Detalles Bibliográficos
Autores principales: Kmiec, Dorota, Iyer, Shilpa S., Stürzel, Christina M., Sauter, Daniel, Hahn, Beatrice H., Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992969/
https://www.ncbi.nlm.nih.gov/pubmed/27531907
http://dx.doi.org/10.1128/mBio.00934-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992969/
https://www.ncbi.nlm.nih.gov/pubmed/27531907
http://dx.doi.org/10.1128/mBio.00934-16

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