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Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance
Human immunodeficiency virus type 1 (HIV-1) groups M, N, O, and P are the result of independent zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting great apes in Africa. Among these, only Vpu proteins of pandemic HIV-1 group M strains evolved potent activity against the restri...
Autores principales: | Kmiec, Dorota, Iyer, Shilpa S., Stürzel, Christina M., Sauter, Daniel, Hahn, Beatrice H., Kirchhoff, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992969/ https://www.ncbi.nlm.nih.gov/pubmed/27531907 http://dx.doi.org/10.1128/mBio.00934-16 |
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